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The clinical evaluation of solid tumors typically includes needle biopsies, which can provide diagnostic (benign vs. cancer) and molecular information (targetable mutations, drug resistance, etc). This procedure has several diagnostic limitations, most notably, the potential to miss the mutations only millimeters away. In response to these limitations, the concept of “liquid biopsy” has emerged in […]View original article

From listening to music to seeing an ultrasound of a baby in the womb, sounds are all around us and are an integral part of our daily life. Many of the sounds we want to hear – such as speaking with a friend at a restaurant – but other sounds (such as conversations at nearby […]View original article

In focused ultrasound surgery (FUS), an ultrasound source radiates pressure waves into the patient’s body to achieve a desired therapeutic effect. FUS has already gained regulatory approval in the U.S. for treating uterine fibroids and pain palliation for bone metastases; other applications – including prostate cancer, liver cancer, and neurosurgery – remain active topics for […]View original article

The cervix, which is the opening into the uterus, is a remarkable organ. It is the only structure in the entire body that has diametrically opposed functions. The normal cervix stays stiff and closed throughout most of pregnancy while the baby develops and then completely softens and opens at just the right time so the […]View original article

Traumatic brain injuries from blast exposure have been called the “signature injury” of military conflicts in Iraq and Afghanistan. This is largely due to our enemies’ unprecedented reliance on explosive weaponry such as improvised explosive devices (IED) (Figure 1). Estimates indicate that approximately 19.5% of deployed military personnel have suffered traumatic brain injuries since 2001 […]View original article

Sonar is a sensing modality that is found in engineering as well as in nature. Man-made sonar systems can be found in places that include the bows of nuclear submarines and the bumpers of passenger cars. Likewise, natural sonar systems can be found in toothed whales that can weigh over 50 tons as well as […]View original article

The siren is a source of sound (or sound transducer) which captures our attention because we know it may emanate from a police vehicle, fire engine, tornado warning tower or other danger warning system. However, there is another reason to heed the siren: it can be a “death ray”! Most of us know of the […]View original article

Many marine and aquatic human activities generate underwater noise and can have potentially adverse effects on the underwater acoustical environment. For instance, loud sounds can affect the migratory or other behavioral patterns of marine mammals [1] and fish [2]. Additionally, if the noise is loud enough, it could potentially have physically damaging effects on these […]View original article